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KMID : 0882419930440060842
Korean Journal of Medicine
1993 Volume.44 No. 6 p.842 ~ p.847
Sjogren's Syndrome Complicated by Distal Renal Tubular Acidosis
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Abstract
istal renal tubular acidosis is a condition characterized by an inability of the distal
nephron to acidify the urine, causing hyperchloremic metabolic acidosis, hypercalciuria,
hypokalemia, nephrocalcinosis, and nephrolithiasis. Both hereditary and aquired forms have
been described, the latter commonly associated with immune-mediated disorders. It has
recetly been noted that diseases charaterized by hyperglobulinemia are occasionally
complicated by renal tubular acidosis, and this combination of hyperglobulinemia and renal
tubular acidosis has been reported in Sjogren's syndrome and other immune-mediated
disorders. Recently we experienced a case of sjogren syndrome of which manifestations were
severe hypokalemia, and other features of distal renal tubular acidosis.
We presents a case of Sjogren's syndrome complicated by renal tubular acidosis with
literature review.
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